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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
5 articles
Newest firstBackgroundCare delivery in conventional health systems is structured around clinical anatomical specialties, often geared towards managing single conditions rather than people. As a result, people with Multiple Long-Term Conditions (MLTC) often need to see many different specialists to manage their health, resulting in fragmented care that is inefficient and costly. Certain Long-term Conditions (LTCs) frequently c…
Open article record in new tab ↗Natural language processing (NLP) is increasingly being applied to obtain unsupervised representations of electronic healthcare record (EHR) data, but their performance for the prediction of clinical endpoints remains unclear. Here we use primary care EHRs from 6,286,233 people with Multiple Long-Term Conditions in England to generate vector representations of sequences of disease development using two input strat…
Open article record in new tab ↗BackgroundCarbapenemase-producing Enterobacterales (CPE) are challenging in the healthcare setting, with resistance to multiple classes of antibiotics and a high associated mortality. The incidence of CPE is rising globally, despite enhanced awareness and control efforts. This study describes an investigation of the emergence of IMP-encoding CPE amongst diverse Enterobacterales species between 2016 and 2019 in pat…
Identifying clusters of co-occurring diseases can aid understanding of shared aetiology, management of co-morbidities, and the discovery of new disease associations. Here, we use data from a population of over ten million people with multimorbidity registered to primary care in England to identify disease clusters through a two-stage process. First, we extract data-driven representations of 212 diseases from patie…
Open article record in new tab ↗BackgroundThe English National Health Service 5-year Forward View emphasises the importance of integration of hospital and community services. Understanding the population a hospital serves is critical to formulating strategies for community engagement and determining their accountability for populations. Existing methods to define catchment areas are unable to adapt to dilute health care markets in urban areas wh…
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