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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
4 articles
Newest firstBackgroundBreakthroughs in model architecture and the availability of data are driving transformational artificial intelligence in healthcare research at an exponential rate. The shift in use of model types can be attributed to multimodal properties of the Foundation Models, better reflecting the inherently diverse nature of clinical data and the advancing model implementation capabilities. Overall, the field is m…
Open article record in new tab ↗Alterations in the excitability of dorsal root ganglion (DRG) neurons are critical in the pathogenesis of acute and chronic pain. Neurotransmitter release from the terminals of DRG neurons is regulated by cannabinoid receptor 1 (CB1) and transient receptor potential vanilloid 1 (TRPV1), both activated by anandamide (AEA). In our experiments, the AEA precursor N-arachidonoylphosphatidylethanolamine (20:4-NAPE) was…
Open article record in new tab ↗BackgroundWith over a thousand FDA-approved artificial intelligence/machine learning-enabled medical devices, research and publications is maturing from focusing on the development and internal validation of models to the external validation of models and implementation trials. Foundation models, especially Large Language Models, have spurred additional aspects of AI research related to healthcare, especially with…
Open article record in new tab ↗Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel, and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in the spinal cord dorsal horn that underlies different pathological pain states. TRPV1 and CB1 receptors share the endogenous agonist anandamide (AEA), produced from N-arachidonoylphosphatidylethanolamine (20:4-NAPE). We investigate…