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19172026

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Author: Ali Asgar Tehrani

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Research Article 2018CC BY-NC-SACC BY-NC-SA allows this article to remain publicly readable here. Reuse is limited to non-commercial use and the recorded source terms.Free full text · non-commercial reuse

The potential effects of hemp seed/evening primrose oils on the mammalian target of rapamycin complex 1 and interferon-gamma genes expression in experimental autoimmune encephalomyelitis.

Soheila Rezapour-Firouzi, Shahram Shahabi, Adel Mohammadzadeh, Ali Asgar Tehrani, Fatemeh Kheradmand, Ebrahim Mazloomi

The mammalian target of rapamycin (mTOR) has a fundamental role in the metabolism, growth, and regulation of the immune system. The interferon gamma (IFN-γ)derived from T helper 1 (Th1) cells is a prominent pro-inflammatory cytokine in multiple sclerosis (MS) and its animal model, the experimental autoimmune encephalomyelitis (EAE). Due to the exclusive role of rapamycin (RAPA) in mTOR complex 1 (mTORC1) inhibitio…

Research in Pharmaceutical Sciences PubMed Central Open Access↗

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