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Research Article 2021CC BYFree full text

Cannabidiol Does Not Cause Significant Changes to Working Memory Performance in the N-Back Task.

Éamon Jones, Styliani Vlachou, Maurizio Bifulco, Simona Pisanti

Cannabis use can be traced back to several centuries before the Common Era, when it was used for industrial, medicinal and recreational purposes. More recently, over 100 different cannabinoid compounds have been identified, one of which is cannabidiol (CBD), a compound widely used for anti-inflammatory and anxiolytic treatment. The literature surrounding the cognitive effects of CBD is limited, with most studies f…

Pharmaceuticals Europe PMC

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Review Article 2020CC BYFree full text

A Critical Review of the Role of the Cannabinoid Compounds Δ9-Tetrahydrocannabinol (Δ9-THC) and Cannabidiol (CBD) and their Combination in Multiple Sclerosis Treatment.

Éamon Jones, Styliani Vlachou, Eric J Downer

Many people with MS (pwMS) use unregulated cannabis or cannabis products to treat the symptoms associated with the disease. In line with this, Sativex, a synthetic combination of cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC) has been approved to treat symptoms of spasticity. In animals, CBD is effective in reducing the amounts of T-cell infiltrates in the spinal cord, suggesting CBD has anti-inflammatory…

Molecules Europe PMC

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