Learning to estimate sample-specific transcriptional networks for 7,000 tumors
Abstract Network estimation is essential for understanding the structure and function of biological systems, but current statistical approaches fail to…
Abstract Network estimation is essential for understanding the structure and function of biological systems, but current statistical approaches fail to…
Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…
Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…
Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…