Abstract One of the ways in which genes can become activated in tumors is by somatic structural genomic rearrangements leading…
Abstract The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome…
Abstract Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular…
Abstract Mitochondria are essential cellular organelles that play critical roles in cancer. Here, as part of the International Cancer Genome…
Abstract Purpose: Cancer of unknown primary is a group of metastatic tumors in which the standard diagnostic workup fails to…