FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites
Abstract FoxP3, the master regulator of Tregs, employs two DNA-binding modes to recognize diverse DNA sequences. It multimerizes on long…
Abstract FoxP3, the master regulator of Tregs, employs two DNA-binding modes to recognize diverse DNA sequences. It multimerizes on long…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-025-03461-8. Article type: Research Article Keywords: Colorectal cancer, Glutamate…
Abstract Background: Although high mobility group box protein 1 (HMGB1) has been researched in relation to cancer in many investigations,…
Abstract Background: Previous studies have indicated that ψ-modified small RNAs play crucial roles in tumor metastasis. However, the ψ-modified small…
Abstract The COVID-19 pandemic presents a major threat to global public health. Several lines of evidence have shown that the…
Abstract Neutrophil extracellular traps (NETs) are produced through ejection of genomic DNA by neutrophils into extracellular space and serve as…
Abstract Objective: Adenosine deaminase (ADA) plays an important role in immune response, which includes two isoenzymes: ADA1 and ADA2. This…
Abstract Background: The optimal treatment of cancer-related malnutrition remains unknown. A single-center prospective cohort study was performed to compare the…
Abstract As an AAA-ATPase, Vps4 is important for function of multivesicular bodies (MVB) sorting pathway, which involves in cellular phenomena…
Abstract Nosiheptide is a parent compound of thiopeptide family that exhibit potent activities against various bacterial pathogens. Its C-terminal amide…