GSK3β as a potential regulator in AML: A pan-cancer multi-omics analysis
Abstract The distinct roles of GSK3 isoforms (GSK3α/β) in tumorigenesis and immune modulation remain poorly characterized across malignancies. We integrated…
Research Article
Prenatal cannabis smoke exposure alters placental development in a murine model of pregnancy
Abstract Cannabis use during pregnancy continues to increase with smoking remaining the most common mode of consumption. While clinical studies…
Synthesis of Isochromans From Anacardic Acids Obtained From Cashew Nutshell Liquid (CNSL) and Their Antimicrobial Activity
Abstract The synthesis of racemic isochromans from cashew nut shell liquid (CNSL) derived anacardic acids is described. Two key steps…
Identification and Expression Analysis of the MLO Gene Family Under Salt Stress in Cotton (Gossypium hirsutum L.)
Abstract MLO (Mildew Resistance Locus O) genes encode seven-transmembrane proteins that function as critical regulators of powdery mildew resistance and…
Multiple omics analyses and experiments validation identify PRDX3 as a biomarker of prognosis and antioncogene in kidney clear cell carcinoma
Abstract Peroxiredoxin 3 (PRDX3), a key mitochondrial redox enzyme, has been implicated in malignant tumor initiation and development. However, the…
Artificial Intelligence in Public Health Education: A Scoping Review of Workforce Competency Development
Abstract Background: Artificial intelligence (AI) has catalyzed profound shifts in public health education, compelling institutions to explore innovative methods to…
In vitro antibacterial, anti-biofilm, anti-quorum-sensing, and cytotoxic activities of leaf crude extracts of Cannabis “Gorilla glue 1”
Abstract The resilience of biofilms makes it challenging to treat bacterial infections using conventional antibiotics. The study aimed to assess…
Effect of Δ9-tetrahydrocannabinol and cannabidiol on myofascial pain modulation in patients with temporomandibular disorder: a prospective crossover study
Abstract Δ9-THC/CBD reduced TMD pain from 7.35 to 3.50 on the VAS scale. Functional gain: mouth opening increased from 45.9…
Multi-dimensional analysis reveals the potential of PDK4 as a tumor biomarker and target for immunotherapy
Abstract Purpose: To explore the clinical significance of pyruvate dehydrogenase kinase 4 (PDK4) in pan-cancer and its potential as a…
Isolation, Antiradical Activity, and Cytotoxicity of Flavonoids From Cunila angustifolia
Abstract Cunila angustifolia (“vassourinha do campo”) is a plant species native to southern Brazil that is traditionally consumed as an…