Methamphetamine Use in People Living with HIV: Clinical, Neurocognitive, and Blood Biomarker Profiles
Abstract Background: Methamphetamine (MA) use in people living with HIV (PLWH) has been linked to neurocognitive and behavioral dysregulation. We…
Research Article
BCTI: a Bayesian network-based method for revealing critical transitions in complex biological systems
Abstract Background: The identification of critical states during disease progression is essential yet challenging for preventing disease deterioration and developing…
Pan-cancer multi-omics profiling of OAS3 reveals its immunological and prognostic associations across human cancers
Abstract Background: The enzyme 2′-5′-oligoadenylate synthetase 3 (OAS3) plays a well-established role in antiviral immunity, but its involvement in cancer…
Mapping the research landscape of minor cannabinoids: a bibliometric analysis of research trends and hotspots
Abstract Background: Minor cannabinoids, including cannabigerol (CBG), cannabinol (CBN), and cannabichromene (CBC), are gaining scientific attention for their distinct therapeutic…
TRMT6/TRMT61A-mediated tRNA m1A modification enhances protein translation and activates the IRE1α–XBP1s pathway to promote anaplastic thyroid cancer progression
Abstract Background: Anaplastic thyroid cancer (ATC) is a highly aggressive malignancy with rapid progression and poor prognosis. Although N1-methyladenosine (m1A)…
Phenolic Profile and Biological Evaluation of Salvia ceratophylloides Ard.: A Novel Source of Rosmarinic Acid
Abstract Salvia ceratophylloides Ard. (Sc), a rare endemic species from Southern Italy, has been chemically unexplored. We report the first…
Exploring perceptions of cannabis use and employment implications among healthcare workers: a single-institution experience
Abstract Background: Cannabis use is becoming increasingly prevalent in the United States, and its implications extend into many facets of…
Developmental Cascades From Prenatal Tobacco, Tobacco-cannabis Co-exposure to Early school-age externalizing Problems
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10802-025-01407-w. Article type: Research Article Keywords: Prenatal tobacco exposure,…
Direct coupling of the human nuclear exosome adaptors NEXT and PAXT with transcription termination and processing machineries
Abstract In human cells, the Nuclear EXosome Targeting (NEXT) and Poly(A) tail eXosome Targeting (PAXT) adaptors direct the nuclear exosome…
Positive face BOLD response and task-dependent ventral striatal functional connectivity during Go/No-go task among abstinent cannabis-using adolescents and young adults
Abstract Introduction: Regular cannabis use is associated with attenuated neural reward signaling, primarily measured through monetary or drug-cue tasks. Yet,…