High-Potency Prenatal Cannabis Exposure and Birth Outcome Measures
Abstract Background/Objectives: Pregnant women have limited information on the impact of prenatal cannabis exposure (PCE) alone. Our aim was to…
Sex differences
Alcohol use and cannabis craving in daily life: Sex differences and associations among young adults
Abstract Background: Alcohol and cannabis are commonly used together by young adults. With frequent pairings, use of one substance may…
Paclitaxel-Associated Mechanical Sensitivity and Neuroinflammation Are Sex-, Time-, and Site-Specific and Prevented through Cannabigerol Administration in C57Bl/6 Mice
Abstract Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent and dose-limiting complications in chemotherapy patients. One identified mechanism…
Δ9-tetrahydrocannabinol discrimination: Effects of route of administration in mice
Abstract We examined if route of administration altered THC’s discriminative stimulus in mice. i.p., p.o., s.c., and aerosolized THC fully…
Association between cannabis use disorder and schizophrenia stronger in young males than in females
Abstract Background: Previous research suggests an increase in schizophrenia population attributable risk fraction (PARF) for cannabis use disorder (CUD). However,…
Chronic Cannabigerol as an Effective Therapeutic for Cisplatin-Induced Neuropathic Pain
Abstract Cannabigerol (CBG), derived from the cannabis plant, acts as an acute analgesic in a model of cisplatin-induced peripheral neuropathy…
Sex differences in acute delta-9-tetrahydrocannabinol (Δ9-THC) response and tolerance as a function of mouse strain
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00213-023-06421-8. Article type: Research Article Keywords: Sex differences, cannabinoids,…
Naturalistic examination of the anxiolytic effects of medical cannabis and associated gender and age differences in a Canadian cohort
Abstract Background: The aim of the current study was to examine patterns of medical cannabis use in those using it…
Sex-dependent differences in the anxiolytic-like effect of cannabidiol in the elevated plus-maze
Abstract Rationale: Cannabidiol (CBD), the major non-psychoactive constituent of cannabis, has therapeutic potential for the treatment of anxiety. Most preclinical…
Sex Differences in the Neuropsychiatric Effects and Pharmacokinetics of Cannabidiol: A Scoping Review
Abstract Cannabidiol (CBD) is a non-intoxicating cannabinoid compound with diverse molecular targets and potential therapeutic effects, including effects relevant to…