A Comprehensive Analysis of Epoxide Hydrolase 2 (EPHX2) in Pan‐Cancer
Abstract Background and Aims: Epoxide hydrolase 2 (EPHX2) regulates lipid signaling across various metabolites by encoding soluble epoxide hydrolase. However,…
immune infiltration
Midnolin Correlates With Anti‐Tumour Immunity and Promotes Liver Cancer Progression Through β‐Catenin
Abstract Midnolin (MIDN) is a protein coding gene that promotes the destruction of transcription factors encoded by immediate‐early genes. Previous…
The expression of autophagy-related gene CXCL12 in endometriosis associated ovarian cancer and pan-cancer analysis
Abstract Background: Endometriosis-associated ovarian cancer (EAOC), an aggressive form of malignant ovarian neoplasm with origins in endometriosis (EM), has risen…
Pan‑cancer analysis of oncogene SFXN1 to identify its prognostic and immunological roles in lung adenocarcinoma
Abstract As cancer incidence and mortality rates continue to rise, the urgency for research in this field has increased globally.…
Characterization of Exhausted T Cell Signatures in Pan-Cancer Settings
Abstract T cells play diverse roles in cancer immunology, acting as tumor suppressors, cytotoxic effectors, enhancers of cytotoxic T lymphocyte…
Pan-Cancer Characterization Identifies SLC19A1 as an Unfavorable Prognostic Marker and Associates It with Tumor Infiltration Features
Abstract Background: Recent studies have identified solute carrier family 19 member 1 (SLC19A1) as a second messenger transporter that regulates…
Multi-omics analysis identifies UBA family as potential pan-cancer biomarkers for tumor prognosis and immune microenvironment infiltration
Abstract Background: UBA1 and UBA6 are classic ubiquitin-activating E1 enzymes, which participate in the ubiquitination degradation of intracellular proteins and…
Comprehensive Analysis of Granzymes and Perforin Family Genes in Multiple Cancers
Abstract Background/Objectives: Cancer remains a significant global health concern, with immunotherapies emerging as promising treatments. This study explored the role…
Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC
Abstract We provide a comprehensive picture of the expression landscape of CDC6 in pan-cancer and its close relationship with the…
Pan-Cancer Analysis Identifies YKT6 as a Prognostic and Immunotherapy Biomarker, with an Emphasis on Cervical Cancer
Abstract Background: Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-mediated membrane fusion is crucial for autophagy, making YKT6, a key modulator…