Endocannabinoid System: Chemical Characteristics and Biological Activity
Abstract The endocannabinoid system (eCB) has been studied to identify the molecular structures present in Cannabis sativa. eCB consists of…
endocannabinoid system
Role of the endocannabinoid system in fragile X syndrome: potential mechanisms for benefit from cannabidiol treatment
Abstract Multiple lines of evidence suggest a central role for the endocannabinoid system (ECS) in the neuronal development and cognitive…
Exploring the Potential of Cannabinoid Nanodelivery Systems for CNS Disorders
Abstract Cannabinoids have a major therapeutic value in a variety of disorders. The concepts of cannabinoids are difficult to develop,…
Impaired Ghrelin Signaling Does Not Lead to Alterations of Anxiety-like Behaviors in Adult Mice Chronically Exposed to THC during Adolescence
Abstract As marijuana use during adolescence has been increasing, the need to understand the effects of its long-term use becomes…
The role of cannabinoids in pain modulation in companion animals
Abstract The use of cannabinoids in both veterinary and human medicine is controversial for legal and ethical reasons. Nonetheless, the…
The function of the endocannabinoid system in the pancreatic islet and its implications on metabolic syndrome and diabetes
Abstract The following review focuses on the scientific studies related to the role of endocannabinoid system (ECS) in pancreatic islet…
Clinical Research Evidence Supporting Administration and Dosing Recommendations of Medicinal Cannabis as Analgesic in Cancer Patients
Abstract The analgesic potential of Cannabis sativa L.—based medicinal cannabis products for treatment of cancer associated chronic pains has gained…
The Endocannabinoid System as a Target for Neuroprotection/Neuroregeneration in Perinatal Hypoxic–Ischemic Brain Injury
Abstract The endocannabinoid (EC) system is a complex cell-signaling system that participates in a vast number of biological processes since…
Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Abstract The endocannabinoid system has been shown to be involved in various skin functions, such as melanogenesis and the maintenance…
A randomized, controlled trial of ZYN002 cannabidiol transdermal gel in children and adolescents with fragile X syndrome (CONNECT-FX)
Abstract Background: Fragile X syndrome (FXS) is associated with dysregulated endocannabinoid signaling and may therefore respond to cannabidiol therapy. Design:…