Anxiety Modulation by Cannabinoids—The Role of Stress Responses and Coping
Abstract Endocannabinoids were implicated in a variety of pathological conditions including anxiety and are considered promising new targets for anxiolytic…
endocannabinoid system
Neuro-Gastro-Cannabinology: A Novel Paradigm for Regulating Mood and Digestive Health
Abstract The maintenance of homeostasis in the gastrointestinal (GI) tract is ensured by the presence of the endocannabinoid system (ECS),…
Pharmacohistory of Cannabis Use—A New Possibility in Future Drug Development for Gastrointestinal Diseases
Abstract Humans have employed cannabis for multiple uses including medicine, recreation, food, and fibre. The various components such as roots,…
Neuroinflammation in the Central Nervous System: Exploring the Evolving Influence of Endocannabinoid System
Abstract Neuroinflammation is a complex biological process that typically originates as a protective response in the brain. This inflammatory process…
Rational Design, Synthesis, and Evaluation of Fluorescent CB2 Receptor Ligands for Live-Cell Imaging: A Comprehensive Review
Abstract The cannabinoid receptors CB1 and CB2 are class A G protein-coupled receptors (GPCRs) that are activated via endogenous lipids…
Individually tailored dosage regimen of full-spectrum Cannabis extracts for autistic core and comorbid symptoms: a real-life report of multi-symptomatic benefits
Abstract Autism Spectrum Disorders (ASD) may significantly impact the well-being of patients and their families. The therapeutic use of cannabis…
Endocannabinoid basis of personality—Insights from animal model of social behavior
Abstract Rationale: The endocannabinoid system is known to be involved in learning, memory, emotional processing and regulation of personality patterns.…
Therapeutic Potential of Cannabinoids in Glaucoma
Abstract Glaucoma is a leading cause of irreversible blindness worldwide. To date, intraocular pressure (IOP) is the only modifiable risk…
Endocannabinoid signaling and epigenetics modifications in the neurobiology of stress-related disorders
Abstract Stress exposure is associated with psychiatric conditions, such as depression, anxiety, and post-traumatic stress disorder (PTSD). It is also…
Long-Term Treatment with Cannabidiol-Enriched Cannabis Extract Induces Synaptic Changes in the Adolescent Rat Hippocampus
Abstract The endocannabinoid system (eCS) is widely distributed in mammalian tissues and it is classically formed by cannabinoid receptors, endogenous…