Abstract The rapid structural evolution and emergence of novel synthetic cannabinoid receptor agonists (SCRAs) in the recreational market remains a…
Abstract Natural and non-natural hexahydrocannabinols (HHC) were first described in 1940 by Adam and in late 2021 arose on the…
Abstract Cannabinoids are compounds isolated from cannabis and are also widely present in both nervous and immune systems of animals.…
Abstract Cannabidiol (CBD) is a potential antidepressant agent. We examined the association between the antidepressant effects of CBD and alterations…
Abstract Endocannabinoid system activity declines with age in the hippocampus, along with the density of the cannabinoid receptor type-1 (CB1).…
Abstract Cannabinoid receptor 1 (CB1R) has been one of the major targets in medication development for treating substance use disorders…
Abstract Neutral antagonists of GPCRs remain relatively rare—indeed, a large majority of GPCR antagonists are actually inverse agonists. The synthetic…
Abstract Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between…
Keywords: Chlorpyrifos, Endocannabinoids, CB1 receptor, Microbiota, Obesogen, Δ Authors: Marilyn H. Silva License: © 2021 The Author(s) CC BY-NC-ND 4.0…
Abstract Reactive impulsive aggression is characterized by outbursts of rage and violence when subjects encounter threatening stressful events. Although impulsive…