A pan-cancer analysis of TNFAIP8L1 in human tumors
Abstract TNFAIP8L1, as a recently identified member in TNFAIP8 family, plays an important role in tumorigenesis. However, a pan-cancer analysis…
Cancer prognosis
Prognostic value and immunological role of cathepsin S gene in pan‑cancer
Abstract The cathepsin S (CTSS) gene encodes a lysine cysteine protease and serves an important role in the development of…
Prognostic significance of Lymphocyte-activation gene 3 (LAG3) in patients with solid tumors: a systematic review, meta-analysis and pan-cancer analysis
Abstract Background: Lymphocyte-activation gene 3 (LAG3) is a recently discovered immune checkpoint molecule that has been linked to immunosuppression and…
Pan-cancer analysis of 60S Ribosomal Protein L7-Like 1 (RPL7L1) and validation in liver hepatocellular carcinoma
Abstract RPL7L1 was found to be aberrantly overexpressed in multiple tumor types such as LIHC, LUAD, COAD, GBM, BRCA, HNSC…
An association between ATP7B expression and human cancer prognosis and immunotherapy: a pan-cancer perspective
Abstract Background: ATP7B is a copper-transporting protein that contributes to the chemo-resistance of human cancer cells. It remains unclear what…
Pan-Cancer Analysis and Validation of Opioid-Related Receptors Reveals the Immunotherapeutic Value of Toll-Like Receptor 4
Abstract Introduction: The relationship between the expression of opioid-associated receptors and cancer outcomes is complex and varies among studies. Methods:…
Oncogene goosecoid is transcriptionally regulated by E2F1 and correlates with disease progression in prostate cancer
Abstract Background: Although some well-established oncogenes are involved in cancer initiation and progression such as prostate cancer (PCa), the long…
Pan-cancer analyses of senescence-related genes in extracellular matrix characterization in cancer
Abstract Purpose: The aged microenvironment plays a crucial role in tumor onset and progression. However, it remains unclear whether and…
A comprehensive analysis of SLC25A1 expression and its oncogenic role in pan-cancer
Abstract Objective: The solute carrier family 25 member 1 (SLC25A1) is currently the only known human transporter for citrate in…
Comprehensive analysis of ZNF692 as a potential biomarker associated with immune infiltration in a pan cancer analysis and validation in hepatocellular carcinoma
Abstract Currently, the roles of ZNF692 have been documented exclusively in lung, colon, and cervical cancers. However, its involvement in…