Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells
Abstract Background/Aim: Mesenchymal stem cells (MSCs) are used to treat various degenerative diseases. However, their therapeutic potential is limited by…
Autophagy
Autophagy and mitophagy in dermatological disease: a comprehensive review from molecular pathways to therapeutic frontiers
Abstract Autophagy – the cell’s built-in recycling and quality-control programme – touches every layer of cutaneous biology. In keratinocytes it…
Metabolic Functions and Mechanisms of Selenium, Selenocysteine, and GPX4 Mediated Immune Regulation Through Autophagy in Solid Tumors
Abstract Selenium, an essential trace element in the human body, is present in the form of selenocysteine (Sec) within 25…
Decoding the Spectrum of Anorexia Nervosa: Clinical Impact, Molecular Insights, and Therapeutic Perspectives
Abstract Anorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among mental illnesses, characterized by an…
SQSTM1/p62 as a prognostic indicator in pancancer and nasopharyngeal carcinoma
Abstract Objective: This study evaluated SQSTM1/p62 expression patterns and its prognostic value across multiple cancers, with a focus on nasopharyngeal…
Cannabidiol (CBD) as a potential therapeutic agent for liver cancer: a comprehensive review of current evidence
Abstract Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality with limited treatment options. Cannabidiol (CBD), a non-psychoactive compound…
The expression of autophagy-related gene CXCL12 in endometriosis associated ovarian cancer and pan-cancer analysis
Abstract Background: Endometriosis-associated ovarian cancer (EAOC), an aggressive form of malignant ovarian neoplasm with origins in endometriosis (EM), has risen…
Cannabidiol-Induced Autophagy Ameliorates Tau Protein Clearance
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s12640-025-00729-3. Article type: Research Article Keywords: CBD,…
EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy
Abstract Background: EMP2 is a tumor-associated membrane protein belonging to the GAS-3/PMP22 gene family. EMP2 expression demonstrates significant tissue specificity…
Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway
Abstract Cannabinoids include both endogenous endocannabinoids and exogenous phytocannabinoids, such as cannabidiol (CBD), and have potential as therapeutic agents in…