Antiproliferative Effects of Cannabinoids and Cisplatin in Cervical Cancer Cells
Abstract Introduction: Cervical cancer remains a leading cause of cancer‐related mortality among women globally, particularly in low‐ and middle‐income countries.…
Autophagy
Exploring cannabinoid modulation on autophagy mechanisms in Alzheimer’s disease: a review
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of toxic protein aggregates in the brain, leading…
Cannabinoid Signaling and Autophagy in Oral Disease: Molecular Mechanisms and Therapeutic Implications
Abstract Autophagy is a well-preserved biological mechanism that is essential for sustaining homeostasis by degradation and recycling damaged organelles, misfolded…
Cannabidiol Enhances SIRT1 and Autophagy for the Maintenance of Human Mesenchymal Stem Cells
Abstract Background/Aim: Mesenchymal stem cells (MSCs) are used to treat various degenerative diseases. However, their therapeutic potential is limited by…
Autophagy and mitophagy in dermatological disease: a comprehensive review from molecular pathways to therapeutic frontiers
Abstract Autophagy – the cell’s built-in recycling and quality-control programme – touches every layer of cutaneous biology. In keratinocytes it…
Decoding the Spectrum of Anorexia Nervosa: Clinical Impact, Molecular Insights, and Therapeutic Perspectives
Abstract Anorexia nervosa (AN) is a severe psychiatric disorder with the highest mortality rate among mental illnesses, characterized by an…
Cannabidiol (CBD) as a potential therapeutic agent for liver cancer: a comprehensive review of current evidence
Abstract Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality with limited treatment options. Cannabidiol (CBD), a non-psychoactive compound…
Cannabidiol-Induced Autophagy Ameliorates Tau Protein Clearance
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s12640-025-00729-3. Article type: Research Article Keywords: CBD,…
Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway
Abstract Cannabinoids include both endogenous endocannabinoids and exogenous phytocannabinoids, such as cannabidiol (CBD), and have potential as therapeutic agents in…
The molecular anti-metastatic potential of CBD and THC from Lebanese Cannabis via apoptosis induction and alterations in autophagy
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-76340-x. Article type: Research Article Keywords: Breast cancer, Cannabinoids,…