Integrated bioinformatic analysis of HNF1A in human cancers
Abstract Objectives: Cancer is a threat to human health, and many molecules are involved in the transformation of malignant cells.…
Advanced cancer
Role of m6A methyltransferase component VIRMA in multiple human cancers (Review)
Abstract N6-Methyladenosine (m6A) modification is one of the most widely distributed RNA modifications in eukaryotes. It participates in various RNA…
Different Cannabis sativa Extraction Methods Result in Different Biological Activities against a Colon Cancer Cell Line and Healthy Colon Cells
Abstract Cannabis sativa is one of the oldest medicinal plants used by humans, containing hundreds of bioactive compounds. The biological…
Teneurins: Role in Cancer and Potential Role as Diagnostic Biomarkers and Targets for Therapy
Abstract Teneurins have been identified in vertebrates as four different genes (TENM1-4), coding for membrane proteins that are mainly involved…
DriverSubNet: A Novel Algorithm for Identifying Cancer Driver Genes by Subnetwork Enrichment Analysis
Abstract Identification of driver genes from mass non-functional passenger genes in cancers is still a critical challenge. Here, an effective…
CD96 Correlates With Immune Infiltration and Impacts Patient Prognosis: A Pan-Cancer Analysis
Abstract Background: Immunotherapy has significantly improved patient outcomes, but encountered obstacles recently. CD96, a novel immune checkpoint expressed on T…
Evaluation and characterization of HSPA5 (GRP78) expression profiles in normal individuals and cancer patients with COVID-19
Abstract HSPA5 (BiP, GRP78) has been reported as a potential host-cell receptor for SARS-Cov-2, but its expression profiles on different…
Transcriptome Analysis of Subcutaneous Adipose Tissue from Severely Obese Patients Highlights Deregulation Profiles in Coding and Non-Coding Oncogenes
Abstract Obesity is a major risk factor for a large number of secondary diseases, including cancer. Specific insights into the…
Construction of a risk map to understand the vulnerability of various types of cancer patients to COVID‐19 infection
Abstract COVID‐19 is leading to a global pandemic and invades human cells via ACE2. ACE2 was found to be abundantly…
Mitofusin-2 modulates the epithelial to mesenchymal transition in thyroid cancer progression
Abstract Here, we investigated the potential roles of Mitofusin-2 (MFN2) in thyroid cancer progression. MFN2 regulates mitochondrial fusion/division in cells…