Pan-cancer analysis reveals SGO1 as a potential cancer prognostic and immunological biomarker
Abstract Shugoshin 1 (SGO1) is primarily known for its critical functions in chromosome segregation during cell division, protecting cohesin complexes…
Science Article
Pan-cancer analysis of UGGT1 in human tumors and experimental validation in breast cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-12619-x. Article type: Research Article Keywords: UGGT1, Cancer, Biomarker,…
AURKB and PI3K/AKT/mTOR pathways converge to regulate TERT expression
Abstract Telomere length maintenance, critical for cancer progression, can be driven by TERT promoter mutations (TERTpMUT), which are markers of…
Phytocannabinoids as Novel SGLT2 Modulators for Renal Glucose Reabsorption in Type 2 Diabetes Management
Abstract Background: Sodium–glucose cotransporter 2 (SGLT2) inhibitors have transformed type 2 diabetes mellitus (T2DM) management by promoting glucosuria, lowering glycated…
Computational-Assisted Development of Molecularly Imprinted Polymers for Synthetic Cannabinoid Recognition
Abstract Synthetic cannabinoids (SCs), a prominent class of new psychoactive substances, pose growing challenges to public health due to their…
Molecular docking of danuglipron uncovers potential crossovers between GLP-1R and the endocannabinoid system
Abstract The targeting of the G-protein coupled receptor (GPCRs) glucagon-like-peptide-1-receptor (GLP-1R) by weight loss medications has become extremely prevalent due…
Tetrahydrocannabinol Intoxication from Food at a Restaurant — Wisconsin, October 2024
Authors: Amanda Kita-Yarbro, Stefanie Moccero, Katie Brobston, Jacob Goebel, Janice Block Banks, Christy Vogt, Casey Schumann, Katarina M. Grande, Julia…
Cannabinoid Derived Product is a Potential Novel Therapeutic for Papillary Thyroid Carcinoma
Abstract Rationale: Papillary thyroid carcinoma (PTC) is the most common thyroid cancer that typically affects women ages 20 to 50,…
An X-linked sex determination mechanism in cannabis and hop
Abstract Sex chromosomes in cannabis and hop were identified a century ago because of their obvious visible differences in size…
UGT2B7-mediated drug–drug interaction between cannabinoids and hydromorphone
Abstract Hydromorphone is a highly potent opioid used to treat severe chronic pain. It is metabolized primarily by UDP-glucuronosyltransferase (UGT)2B7…