An X-linked sex determination mechanism in cannabis and hop
Abstract Sex chromosomes in cannabis and hop were identified a century ago because of their obvious visible differences in size…
Science Article
UGT2B7-mediated drug–drug interaction between cannabinoids and hydromorphone
Abstract Hydromorphone is a highly potent opioid used to treat severe chronic pain. It is metabolized primarily by UDP-glucuronosyltransferase (UGT)2B7…
Development of a cannabis health literacy questionnaire: preliminary validation using the Rasch model
Abstract Background: As cannabis becomes more integrated into Canadian society for medical and non-medical purposes, public health efforts have aimed…
Application of Mendelian randomization and bioinformatic analysis to construct a prognostic model for thyroid cancer and perform pan-cancer analysis
Abstract Objective: This study aimed to identify causal effects and potential molecular mechanisms of genes associated with THCA development. Methods:…
The Role of the Endocannabinoid System in Oncology and the Potential Use of Cannabis Derivatives for Cancer Management in Companion Animals
Abstract Companion animals are more and more becoming considered family members, and their owners wish to offer them the same…
Phytochemical Modulators of Nociception: A Review of Cannabis Terpenes in Chronic Pain Syndromes
Abstract Cannabis sativa L. is a phytochemically rich plant with therapeutic potential across various clinical domains, including pain, inflammation, and…
Polymers and immersion time shape bacterial pathogen and antibiotic resistance profiles in aquaculture facilities
Abstract Most equipment used in aquaculture farms is made of plastic. Plastics-associated biofilms may contain potential human pathogenic bacteria (PHPB)…
Phosphoglycerate kinase 1 as a potential prognostic biomarker in papillary thyroid carcinoma
Abstract Backgroud: Papillary thyroid carcinoma (PTC) represents a malignant epithelial tumor characterized with a preference for younger individuals. Despite its…
Large-Scale Profiling of Coding and Long Noncoding Transcriptomes in the Hippocampus of Mice Acutely Exposed to Vaporized CBD or THC
Abstract Cannabis vaping, particularly involving cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), rapidly delivers highly concentrated cannabinoids to the brain, potentially affecting…
Timing matters: modeling the effects of gestational cannabis exposure on social behavior and microglia in the developing amygdala
Abstract Cannabis is the most frequently used illicit drug during pregnancy, with use steadily increasing in the United States as…