Hallmarks of primary headache: part 3 – cluster headache
Abstract Background: Cluster headache (CH) is a rare primary headache disorder characterized by recurrent episodes of strictly unilateral excruciating pain…
Science Article
Minor Cannabinoids CBD, CBG, CBN and CBC differentially modulate sensory neuron activation
Abstract The use of minor cannabinoids has been advanced, in part, by the idea of providing relief from pain and…
SADI-S and SG surgeries induce distinct bile acid profiles linked to improved glucose metabolism via microbiota interactions
Abstract Introduction: Although bariatric surgery profoundly ameliorates type 2 diabetes (T2D), the mechanisms whereby specific procedures confer metabolic benefits through…
Clozapine rechallenge after clozapine-induced myocarditis: A case report to validate a previously published protocol
Abstract Introduction: Clozapine is an effective antipsychotic indicated for treatment-resistant schizophrenia (TRS). Its use is limited by its extensive adverse…
Piperacillin reaches high concentrations in bile and target tissues of the biliary system: an experimental study in pigs
Abstract The antibiotic combination of piperacillin/tazobactam (TZP) is commonly utilized for preventing and treating infections in the biliary system, with…
Field Explosives Detectors—Current Status and Development Prospects
Abstract Highlights: What are the main findings? What is the implication of the main finding? Abstract: This review critically evaluates…
The microbiota–gut–brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention
Abstract The microbiota–gut–brain axis (MGBA) is increasingly recognized as a critical regulator of brain health, influencing both neurodevelopment and age-related…
Prioritizing cancer therapeutic genes using BioRank: A biologically-informed PageRank framework
Abstract The identification of therapeutic target genes constitutes a critical yet challenging aspect of cancer research, primarily due to the…
Constructing a Pan-Cancer Prognostic Model via Machine Learning Based on Immunogenic Cell Death Genes and Identifying NT5E as a Biomarker in Head and Neck Cancer
Abstract Immunogenic cell death (ICD) is a specialized form of cell death that triggers antitumor immune responses. In tumors, ICD…
Effect of immune-related intratumoral microbiota and host gene expression on cancer prognosis
Abstract IMPORTANCE: The intratumoral microbiota is a vital part of the tumor microenvironment, yet its interplay with host gene expression…