Fermented Plant-Derived Phytoconstituents in Biocosmetics: Pharmacological Enhancements and Applications

Abstract The application of plant-derived extracts in dermatological and cosmeceutical formulations is often limited by poor bioavailability, low skin permeability, and the instability of bioactive compounds. Fermentation has emerged as a promising biotechnological approach to enhance phytochemical composition and biological activity through microbial biotransformation. This review aims to critically evaluate the effects of fermentation on plant-derived phytoconstituents and their relevance in cosmeceutical dermatology. A structured literature search was conducted using Scopus and PubMed databases for studies published between 2015 and