SQSTM1/p62 as a prognostic indicator in pancancer and nasopharyngeal carcinoma
Abstract Objective: This study evaluated SQSTM1/p62 expression patterns and its prognostic value across multiple cancers, with a focus on nasopharyngeal…
Science Article
A Systematic Review of Management of Cramping Pain in Patients with Amyotrophic Lateral Sclerosis
Abstract Introduction: Pain, particularly cramping, in people living with amyotrophic lateral sclerosis (ALS) is often underrecognized and under-treated. Despite affecting…
Importance of PERK pathway modulation on colorectal cancer management: a systematic review
Abstract Background: The protein kinase RNA-like endoplasmic reticulum kinase (PERK) branch of the Unfolded Protein Response (UPR) plays a complex…
Natural Products Inhibit Bacterial Growth and Modulate Quorum‐Sensing Systems Las and Rhl in Pseudomonas aeruginosa PA14
Abstract Quorum sensing (QS) is a bacterial cell communication system in Pseudomonas aeruginosa, which regulates the production of several virulence…
Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization
Abstract Many pathogenic bacteria use proteinaceous ethanolamine utilization microcompartments (Eut BMCs) to catabolize ethanolamine. This ability gives pathogens a competitive…
FBXL22, a circadian-regulated immune biomarker with pan-cancer prognostic value and therapeutic potential in prostate cancer
Abstract F-box and leucine-rich repeat protein 22 (FBXL22) has been implicated in breast and prostate cancer types; however, comprehensive pan-cancer…
Comprehensive bioinformatics analysis reveals prognostic significance and immunological roles of WNT gene family in breast cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13315-6. Article type: Research Article Keywords: WNTs, Breast cancer,…
MicroRNA signatures of cancer risk in kidney transplant patients: insights from the COMETA study
Abstract Background: Post-transplant malignancies are one of the leading causes of morbidity, mortality and graft failure in kidney transplant recipients…
TPD52 promotes the proliferation and metastasis of gastric cancer cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12876-025-04295-y. Article type: Research Article Keywords: TPD52, Gastric cancer,…
SADI-S and SG surgeries induce distinct bile acid profiles linked to improved glucose metabolism via microbiota interactions
Abstract Introduction: Although bariatric surgery profoundly ameliorates type 2 diabetes (T2D), the mechanisms whereby specific procedures confer metabolic benefits through…