Cell-Free Synthesis of Cannabistilbene I: A Dual Acting Anti-Inflammatory from Cannabis sativa
Abstract Despite the potential of Cannabis bibenzyls to remedy acute and chronic inflammation, their relative scarcity, in planta, has hindered…
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Transcriptomic and functional responses of human airway cells to vaped ∆8-THC and its oxidation product ∆8-THCQ
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-53356-z. Article type: Research Article Keywords: Cell biology, Diseases,…
What Do Thirty Years of Neuroimaging Research Tell Us About Recreational Cannabis Use and Brain Integrity? A Narrative Review of the Multimodal Neuroimaging Evidence to Date
Abstract The consumption of cannabinoids is highly prevalent and has been associated with altered structural, functional, and metabolic brain integrity,…
Prognostic and therapeutic implications of PSMD14 in hepatocellular carcinoma: an integrative analysis of transcriptomic and single-cell profiles
Abstract Background: Liver hepatocellular carcinoma (LIHC) represents a common and aggressive malignancy characterized by an unfavorable clinical outcome, highlighting an…
The association between state cannabis legalization and non-fatal opioid poisonings among adults with employer-sponsored insurance in the United States
Abstract Objective: Although many states have legalized medical and recreational cannabis, its association with non-fatal opioid poisonings remains unclear. This…
Suicide attempts among youth attending special education centres: risk and protective factors
Abstract Purpose: Adolescents studying in special education centres are a group at particular risk of suicidal behaviour. The aim of…
Genetic Pathways Point to the Biology Underlying the Association Between Cannabis Use Disorder and Psychosis
Abstract Background: Cannabis use is associated with increased risk of psychotic disorders, but the underlying biological mechanisms remain unclear. We…
Integrated pan cancer analysis with breast cancer validation identifies SEC13 homolog as prognostic biomarker and immunotherapy target
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-52775-2. Article type: Research Article Keywords: Pan-cancer, Prognosis, Diagnosis,…
Immunomodulatory effects of cannabis use: a multi-omics study in people living with HIV
Abstract Background: Cannabis is one of the most commonly used substances worldwide. Cannabinoids are known to have anti-inflammatory effects. However,…
Pan-cancer investigation identifies ARL4A as a prospective therapeutic indicator for thyroid cancer
Abstract Background: ADP-ribosylation factor-like 4 A (ARL4A), a small GTPase involved in cytoskeletal dynamics and signal transduction, exhibits dysregulated expression…