The silent strain beyond the screen: conceptualizing digital compassion fatigue in nursing
Abstract Background: The integration of digital technologies into healthcare has transformed the way nurses deliver care. While these advancements improve…
Members
Latent Profile Analysis of Moral Sensitivity and Influencing Factors Among Nursing Students in China
Abstract Aim: This study aimed to analyse the latent profiles of moral sensitivity of nursing students and to explore the…
Cannabinoid receptor 2 affect the inflammatory response in periodontitis by regulating macrophage M1/M2 polarization
Abstract Objective: This study investigated the effect of cannabinoid receptor 2 (CB2R) on macrophage polarization and inflammatory severity in periodontitis,…
A comprehensive pan-cancer analysis of the prognostic role and immunotherapy efficacy evaluation of Glyoxalase 1
Abstract Background: Glyoxalase 1 (GLO1), an enzyme responsible for breaking down methylglyoxal (MG), is increasingly recognized as a tumor-promoting factor…
Traditional Chinese medicine on epilepsy: focus on N-methyl-D-aspartate receptors and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors
Abstract N-methyl-D-aspartate receptors (NMDARs) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) mediate the majority of excitatory synaptic transmission in central nervous system.…
Design and Preclinical Evaluation of First 68Ga-Labeled Cathepsin D‑Targeted Radiotracers
Abstract Cathepsin D (CTSD), a lysosomal aspartic protease linked to cancer progression and poor patient outcomes, is underexplored as a…
MCRS1 is associated with immunosuppressive microenvironments in pan-cancer and promotes hepatocellular carcinoma malignant phenotypes
Abstract Background: Pan-cancer analyses focused on the immunological significance and therapeutic potential of microspherule protein 1 (MCRS1) remain unreported. This…
Identification of ITGA2 as a methylation-regulated oncogene through a CeRNA network in papillary thyroid carcinoma
Abstract Objective: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. This study aimed to construct a competing endogenous…
Conkazal-M1 from the MKAVA family of conotoxins – a dual-function protease inhibitor and neuroactive peptide
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high…
A pancancer analysis reveals the oncogenic role of glutaminase 1 (GLS1) in tumor metabolism and immune evasion: a bioinformatics analysis
Abstract Background: Metabolic reprogramming is a significant factor that regulates the function and differentiation of immune cells, thereby influencing the…