Association Between Cannabis Use and Tinnitus: A Multi‐Center Propensity‐Score‐Matched Cohort Study
Abstract Objective: There are mixed findings regarding the impact of cannabis use on tinnitus, with different patterns of cannabis use…
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Pan-cancer multi-omic integration of Trop2 reveals biological determinants and translational implications for ADC therapy
Abstract Trop2–directed antibody-drug conjugates (ADCs) show activity across epithelial cancers, yet determinants of target expression in tumors and normal tissues…
Interpol review of forensic toxicology, 2023–2025
Authors: Stephen Chi-yuen Ip, Chun-wa Chan, Chun-wo Chan, Anlea Chu, Wai-wah Chung, Janesse Wing-sze Hui, Ka-Wai Ku, Wing-sze Lee, Kam-moon…
Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives
Abstract Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for their inhibition of monoamine oxidases and cholinesterases. Most…
Cannabis and Cannabinoid-Related Suspected Adverse Drug Reactions: Global Patterns and Cross-National Analysis Based on VigiBase® Data
Abstract Background and Objectives: Despite increasing global use of cannabis and cannabinoids, comprehensive data on their safety profile remain limited.…
Pan-Cancer Analysis of a Depression-Related Gene Signature Identifies an Immunosuppressive Tumor Microenvironment and Links to Immunotherapy Response in Breast Cancer
Abstract Background: Depression has been increasingly associated with cancer progression and patient outcomes, yet its molecular and immunological correlates within…
Phytochemical Profiling, Antiplatelet Potential, and Cytotoxic Assessment of Thymelaea tartonraira Aerial Part Essential Oil: In Vitro and In Silico Studies
Abstract This study evaluates the antiplatelet potential of Thymelaea tartonraira essential oil, obtained from aerial parts by hydrodistillation. GC–MS analysis…
Bromination of Cannabinoids from Cannabis sativa L.: A Comparative Study Using an Enzymatic Catalysis Approach
Abstract An in-depth study on bromination of six typical cannabinoids from Cannabis sativa L. is reported using three different methods:…
Cannabidiol attenuates chemotherapy-induced peripheral neuropathic pain through a mechanism that requires the enzyme N -acylphosphatidylethanolamine-specific phospholipase D (NAPE-PLD)
Abstract Cannabidiol (CBD) is a non-psychoactive component of cannabis that has been studied as a potential therapy for chronic pain.…
The Prevalence of Substance Use Among Students and Associated Factors: A Systematic Review With Narrative Synthesis
Abstract Background and Aims: Substance use is a major public health and social problem that affects individuals of all ages,…