Multiomics analysis of tumor mutational burden across cancer types
Keywords: Tumor mutational burden (TMB), Molecular alterations, Differential expression, Signaling pathway, Immunology, Survival Authors: Lin Li, Long Bai, Huan Lin,…
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Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling suppression in Caco‐2 cell line
Abstract Given the abundancy of angiotensin converting enzyme 2 (ACE‐2) receptors density, beyond the lung, the intestine is considered as…
The Revolution Will Be Hard to Evaluate: How Co-Occurring Policy Changes Affect Research on the Health Effects of Social Policies
Abstract Extensive empirical health research leverages variation in the timing and location of policy changes as quasi-experiments. Multiple social policies…
Clinical Outcome Data of First Cohort of Chronic Pain Patients Treated With Cannabis‐Based Sublingual Oils in the United Kingdom: Analysis From the UK Medical Cannabis Registry
Abstract Cannabis‐based medicinal products (CBMPs) are an emerging therapeutic option in the management of primary chronic pain, using the role…
Striatal networks for tinnitus treatment targeting
Abstract Neuromodulation treatment effect size for bothersome tinnitus may be larger and more predictable by adopting a target selection approach…
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels
Abstract Significance Statement: Glutamate receptors play important roles in virtually all aspects of brain function and are either involved in…
Comparison of CBD and Cannabis Use Motives
Abstract Cannabidiol, also known as CBD, has increasingly gained popularity as a cure-all product and is now found in products…
Assessing Cannabis Use Disorder in Medical Cannabis Patients: Interim Analyses from an Observational, Longitudinal Study
Abstract Background: To date, no studies have directly assessed potential cannabis use disorder (CUD) in medical cannabis (MC) patients pre-…
A pan-cancer analysis of the oncogenic role of Keratin 17 (KRT17) in human tumors
Abstract Background: Although new evidence from cells or animals suggests a relationship between Keratin 17 (KRT17) and cancer, no pan-cancer…
Analgesic Potential of Terpenes Derived from Cannabis sativa
Abstract Significance Statement: Decades of research have improved our knowledge of cannabis polypharmacy and contributing phytochemicals, including terpenes. Reform of…