CB1 Cannabinoid Receptor Signaling and Biased Signaling
Abstract The CB1 cannabinoid receptor is a G-protein coupled receptor highly expressed throughout the central nervous system that is a…
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The Effect of Medical Cannabis on Pain Level and Quality of Sleep among Rheumatology Clinic Outpatients
Abstract Introduction: Medical cannabis (MC) is becoming increasingly popular for the treatment of chronic pain conditions. In this study, we…
Cannabinoid use and effects in patients with epidermolysis bullosa: an international cross-sectional survey study
Abstract Background: Epidermolysis bullosa (EB) patient anecdotes and case reports indicate that cannabinoid-based medicines (CBMs) may alleviate pain and pruritus…
Effective Utilisation of Halophyte Biomass from Saline Soils for Biorefinering Processes
Abstract The salinity of European soil is increasing every year, causing severe economic damage (estimated 1–3 million hectares in the…
Cannabis against chronic musculoskeletal pain: a scoping review on users and their perceptions
Abstract Background: Chronic musculoskeletal pain (CMP) may lead to reduced physical function and is the most common cause of chronic…
Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
Abstract The use of cannabidiol (CBD) for animal species is an area of growing interest, for example for its anti-inflammatory…
Effectiveness, Safety, and Tolerability of Nabiximols Oromucosal Spray vs Typical Oral Long-Acting Opioid Analgesics in Patients with Severe Neuropathic Back Pain: Analysis of 6-Month Real-World Data from the German Pain e-Registry
Abstract Objective: To compare the effectiveness, safety, and tolerability of add-on nabiximols (NBX) oromucosal spray vs typical oral long-acting opioid…
Binge-like Alcohol Exposure in Adolescence: Behavioural, Neuroendocrine and Molecular Evidence of Abnormal Neuroplasticity… and Return
Abstract Binge alcohol consumption among adolescents affects the developing neural networks underpinning reward and stress processing in the nucleus accumbens…
Altered relationship between cortisol response to social stress and mediotemporal function during fear processing in people at clinical high risk for psychosis: a preliminary report
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00406-021-01318-z. Article type: Research Article Keywords: Clinical high risk,…
Molecular and Biochemical Insights Into Early Responses of Hemp to Cd and Zn Exposure and the Potential Effect of Si on Stress Response
Abstract With the intensification of human activities, plants are more frequently exposed to heavy metals (HM). Zinc (Zn) and cadmium…