Determination of Prenatal Substance Exposure Using Meconium and Orbitrap Mass Spectrometry
Abstract The aim of this study was to develop and to validate a toxicological untargeted screening relying on LC-HRMS in…
Free
Treatment of Glaucoma with Natural Products and Their Mechanism of Action: An Update
Abstract Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by increased intraocular pressure, which…
GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries
Abstract GPR18 receptor protein was detected in the heart and vasculature and appears to play a functional role in the…
Metabolites of Cannabis Induce Cardiac Toxicity and Morphological Alterations in Cardiac Myocytes
Abstract Cannabis is one of the most commonly used recreational drugs worldwide. Rrecent epidemiology studies have linked increased cardiac complications…
Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
Abstract Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding…
Characterisation of Hemp Fibres Reinforced Composites Using Thermoplastic Polymers as Matrices
Abstract Hemp fibres used as a reinforcing agent and three polymeric matrices (polypropylene, bicomponent, recycled polyester) were used to obtain…
Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use
Abstract Benzodiazepines (BZDs) represent one of the most widely used groups of pharmaceuticals, but if used for long periods of…
Metabolomic Fingerprint of Behavioral Changes in Response to Full-Spectrum Cannabis Extracts
Abstract Numerous existing full-spectrum cannabis extract products have been used in clinical trials for the treatment of various diseases. Despite…
Receptor-targeted nanoparticles modulate cannabinoid anticancer activity through delayed cell internalization
Abstract Δ9-tetrahydrocannabinol (Δ9-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including…
Production of Particleboard Using Various Particle Size Hemp Shives as Filler
Abstract Research was performed into the use of hemp shive as a fast-growing and carbon-storing agricultural waste material in the…