Adverse Effects of Non-Medical Use of Cannabis or Opioids Associated with Adverse Childhood Experiences
Abstract Highlights: Public health relevance—How does this work relate to a public health issue? Public health significance—Why is this work…
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Through the haze: a multinational cross-sectional comparison of cannabis risk knowledge gaps among young adults
Abstract Background: Young adults report heightened cannabis use yet show gaps in cannabis-related risk knowledge. Risk knowledge gaps in young…
Hemp Seed Hull and Cellulose Acetate Thermoplastic Biocomposites and Their Properties
Abstract The study explores the potential of thermoplastic biocomposites made from cellulose acetate, modified hemp seed hull particulate fillers and…
Species-Specific Effects of Humic Substances and Mycorrhiza on Antioxidant Defense and Metal Stress Tolerance in Cannabis sativa, Sorghum sudanense × bicolor, and Miscanthus × giganteus Under Field Conditions
Abstract Abiotic stresses, including heavy metal contamination, can severely impair plant growth and antioxidative defense. However, their adverse effects may…
Hematological Inflammatory Indices and Coagulation Parameters in Individuals with Substance Use Disorder: A Comparative Study with Healthy Controls
Abstract Background: Substance use disorder (SUD) is associated with systemic inflammatory activation and may influence hematological and coagulation-related pathways. Chronic…
Dispersive micro-solid-phase extraction coupled to UHPLC-Q-TOF-MS and UHPLC-QqQ-MS for suspect and target screening of illicit drugs and pharmaceuticals in wastewater
Abstract Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s00216-026-06520-3. Article type: Research Article Keywords: Illicit…
Decoding the antihypertensive mechanism of cannabidiol through integrative bioinformatics and machine learning
Abstract Background: Hypertension (HTN) results from intricate molecular mechanisms, making clinical remission difficult to achieve. This study explores the molecular…
Cannabidiol potentiates olaparib-induced cytotoxicity through cell cycle arrest and DNA damage modulation in breast cancer cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s11010-026-05550-w. Article type: Research Article Keywords: TNBC, Breast Cancer,…
The Synthetic Cannabinoid AKB-48 Induces Cell Death in Murine Cerebellum Through Different Signaling Pathways
Abstract Novel psychoactive substances (NPSs) exhibit extremely strong pharmaco-toxicological activity, often leading to severe adverse effects that pose a serious…
Lactic acid promotes metastasis of papillary thyroid carcinoma by enhancing CPT1A lactylation
Abstract Papillary thyroid carcinoma (PTC), the most prevalent thyroid malignancy, exhibits aggressive behavior in subsets with metastasis. Despite advances in…