Cannabinoid inhibition of mechanosensitive K+ channels
Abstract Cannabidiol (CBD) is a prominent non-psychoactive small molecule produced by cannabis plants used clinically as an antiepileptic. Here, we…
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Neural basis of adolescent THC-induced potentiation of opioid responses later in life
Abstract Use of one addictive drug typically influences the behavioral response to other drugs, either administered at the same time…
Case report: Treatment of non-medical tetrahydrocannabinol toxicosis with transmucosal cannabidiol-infused dissolving sheets in six dogs
Abstract Increased cases of canine tetrahydrocannabinol (THC) toxicosis have been reported in North America in recent years. Cases are often…
Cannabidiol effects in stem cells: A systematic review
Abstract Stem cells play a critical role in human tissue regeneration and repair. In addition, cancer stem cells (CSCs), subpopulations…
Recommendations for recognizing and diagnosing Acute Hepatic Porphyria in atypical patient populations
Abstract Background: Acute Hepatic Porphyria is a group of four rare genetic but treatable diseases that often go undiagnosed due…
Aquaphotomics study of fresh cannabis inflorescence: near infrared spectral analysis of water matrix structures
Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s00216-024-05685-z. Article type: Research Article Keywords: Wet,…
Influence of Lignin Type on the Properties of Hemp Fiber-Reinforced Polypropylene Composites
Abstract Increasing environmental awareness has boosted interest in sustainable alternatives for binding natural reinforcing fibers in composites. Utilizing lignin, a…
The Endocannabinoid Activity Remodulation for Psychosis Liability in Youth (EARLY) Study: An Open-Label Feasibility Trial of Ultramicronized-Palmitoylethanolamide Oral Supplementation in Clinical High-Risk State for Psychosis
Abstract To date, no psychotropic medication has shown to effectively halt progression to psychosis among individuals at Clinical High-Risk for…
The Role of Hypothalamic Microglia in the Onset of Insulin Resistance and Type 2 Diabetes: A Neuro-Immune Perspective
Abstract Historically, microglial activation has been associated with diseases of a neurodegenerative and neuroinflammatory nature. Some, like Alzheimer’s disease, Parkinson’s…
A Preliminary Investigation into the Use of Cannabis Suppositories and Online Mindful Compassion for Improving Sexual Function Among Women Following Gynaecological Cancer Treatment
Abstract Background and Objectives: The impact of gynaecological cancer and its treatments on sexual intimacy can be profound on female…