Plant cannabinoids

11-Hydroxy-Delta(9)-tetrahydrocannabinol

A phytocannabinoid that is Δ9-tetrahydrocannabinol in which the methyl group at C-11 has been hydroxylated . Major metabolite of Δ9-tetrahydrocannabinol.

Definition: CHEBI:77270 · Chemical Entities of Biological Interest · release 253

32public articles

3registered condition areas

All documents →

Identity & provenance

Chemical identity

C21H30O3 · molecular weight 330.468

Sources: ChEBI · 253 PubChem computed properties · pug-d1260cdde0a82e49

0 referenced plant-occurrence records. They are identity candidates, not clinical evidence.

Research areas

Conditions found alongside this compound

Document links and organism occurrence are candidates, not proof of efficacy, safety or a treatment recommendation.

Epilepsy and cannabinoids

1 matching public articles

Candidate association · not a treatment claim

Chronic pain and cannabinoids

2 matching public articles

Candidate association · not a treatment claim

Cancer pain and cannabinoids

1 matching public articles

Candidate association · not a treatment claim

Linked local records

Medicines and registered studies

Links use source-reported active ingredients or study intervention names and remain candidates, not treatment claims.

Medicines with this active ingredient

No public medicine record matched.

Registered studies

0 exact source-intervention matches.

No registered study intervention matched.

Recent research

2026

Validation of a microsampling-compatible liquid-liquid extraction method for cannabinoid quantitation in 50 µL of whole blood using liquid chromatography-mass spectrometry.

Journal of Analytical Toxicology · Free full text · non-commercial reuse

2026

Driving by frequent cannabis users 'the morning after' last use of smoked cannabis: an observational driving simulator study.

Journal of Cannabis Research · Free full text

2026

Cognitive performance and subjective effects the morning after last use of smoked cannabis by adults who use cannabis frequently: An observational study.

Drug and Alcohol Dependence Reports · Free full text · non-commercial reuse

2026

Impact of CBD and hemp oil use on drug test results: a systematic review.

International Journal of Legal Medicine · Free full text

2025

Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs.

Frontiers in Veterinary Science · Free full text

2025

Quantification of ∆9-tetrahydrocannabinol, 11-OH-THC, THC-COOH, hexahydrocannabinol, and cannabidiol in human plasma and blood by liquid chromatography-tandem mass spectrometry.

Journal of Analytical Toxicology · Free full text

11-Hydroxy-Delta(9)-tetrahydrocannabinol

Chemical identity

Conditions found alongside this compound

Epilepsy and cannabinoids

Chronic pain and cannabinoids

Cancer pain and cannabinoids

Medicines and registered studies

Medicines with this active ingredient

Registered studies

Recent research

Validation of a microsampling-compatible liquid-liquid extraction method for cannabinoid quantitation in 50 µL of whole blood using liquid chromatography-mass spectrometry.

Driving by frequent cannabis users 'the morning after' last use of smoked cannabis: an observational driving simulator study.

Cognitive performance and subjective effects the morning after last use of smoked cannabis by adults who use cannabis frequently: An observational study.

Impact of CBD and hemp oil use on drug test results: a systematic review.

Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs.

Quantification of ∆9-tetrahydrocannabinol, 11-OH-THC, THC-COOH, hexahydrocannabinol, and cannabidiol in human plasma and blood by liquid chromatography-tandem mass spectrometry.

Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta-9-Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes.

Enhancing cannabinoid bioavailability: a crossover study comparing a novel self-nanoemulsifying drug delivery system and a commercial oil-based formulation.

Tetrahydrocannabivarin (THCV) Dose Dependently Blocks or Substitutes for Tetrahydrocannabinol (THC) in a Drug Discrimination Task in Rats.

Validation of a Microsampling-Compatible LC-MS/MS Method for Cannabinoid Quantitation in Whole Blood

Fatty acid binding protein 7 plays an important modulatory sex-dependent role on brain endocannabinoid levels and THC metabolism.

Cannabinoid-Induced Inhibition of Morphine Glucuronidation and the Potential for In Vivo Drug-Drug Interactions.