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Research Article 2024CC BYFree full text

Cannabidiol Exposure During Rat Pregnancy Leads to Labyrinth-Specific Vascular Defects in the Placenta and Reduced Fetal Growth.

Sofia Allen, Bryony V Natale, Alexis O Ejeckam, Kendrick Lee, Daniel B Hardy, David RC Natale

Introduction: Cannabis use is increasing among pregnant people, and cannabidiol (CBD), a constituent of cannabis, is often perceived as "natural" and "safe" as it is non-intoxicating. In utero, cannabis exposure is associated with negative health outcomes, including fetal growth restriction (FGR). The placenta supplies oxygen and nutrients to the fetus, and alterations in placental development can lead to FGR. Whi…

Cannabis and Cannabinoid Research Europe PMC

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Research Article 2024-01-09CC BY-NCFree full text · non-commercial reuse

Widely accessible prognostication using medical history for fetal growth restriction and small for gestational age in nationwide insured women

Herdiantri Sufriyana, Fariska Zata Amani, Aufar Zimamuz Zaman Al Hajiri, Yu-Wei Wu, Emily Chia-Yu Su

ObjectivesPrevention of fetal growth restriction/small for gestational age is adequate if screening is accurate. Ultrasound and biomarkers can achieve this goal; however, both are often inaccessible. This study aimed to develop, validate, and deploy a prognostic prediction model for screening fetal growth restriction/small for gestational age using only medical history. MethodsFrom a nationwide health insurance da…

medRxiv