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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
2 articles
Newest firstAbstractBackgroundObservational studies have found Attention Deficit Hyperactivity Disorder (ADHD) to be associated with an increased risk of adverse outcomes as well as with early risk factors; however it is not clear whether these associations reflect causal effects. Alternatives to traditional observational studies are needed to investigate causality: one such design is Mendelian randomization (MR), which uses…
Open article record in new tab ↗Background and AimsInitial use of drugs such as tobacco and alcohol may lead to subsequent more problematic drug use - the gateway hypothesis. However, observed associations may be due to a shared underlying risk factor, such as trait impulsivity. We used bidirectional Mendelian Randomisation (MR) to test the gateway hypothesis. DesignOur main method was inverse-variance weighted (IVW) MR, with other methods inclu…
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