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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
3 articles
Newest firstSimple SummaryThis article reviews the roles of lipid mediators as potential therapeutic targets in prostate cancer. Lipid mediators are derived from more complex cellular phospholipids and some come from the diet. The major mediators discussed are sphingosine 1-phosphate, lysophosphatidic acid, prostaglandin E2, thromboxane A2, lipoxin A4, endocannabinoids, and omega-3 fatty acids. All activate distinct druggable…
Open article record in new tab ↗Eosinophils are important effector cells involved in allergic inflammation. When stimulated, eosinophils release a variety of mediators initiating, propagating, and maintaining local inflammation. Both, the activity and concentration of secreted and cytosolic phospholipases (PLAs) are increased in allergic inflammation, promoting the cleavage of phospholipids and thus the production of reactive lipid mediators. Eo…
Open article record in new tab ↗Fatty acids are involved in T cell biology both as nutrients important for energy production as well as signaling molecules. In particular, polyunsaturated fatty acids are known to exhibit a range of immunomodulatory properties that progress through T cell mediated events, although the molecular mechanisms of these actions have not yet been fully elucidated. Some of these immune activities are linked to polyunsatu…
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