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Research Article 2021CC BYFree full text

Hair-based biomarkers in women with major depressive disorder: Glucocorticoids, endocannabinoids, N-acylethanolamines, and testosterone.

Alexander Behnke, Anja M. Gumpp, Aniko Krumbholz, Alexandra M. Bach, Gustav Schelling, Iris-Tatjana Kolassa +1 more

Background Stress-related alterations in the regulation of several endocrine systems, including the hypothalamus-pituitary-adrenal (HPA) and -gonadal (HPG) axes and the endocannabinoid system are proposed to be involved in the etiology of major depressive disorder (MDD). Therefore, this study examines whether altered concentrations of glucocorticoids, testosterone, endocannabinoids, and related N-acylethanolamines…

Comprehensive Psychoneuroendocrinology Europe PMC

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Research Article 2020CC BYFree full text

Associating Emergency Medical Services personnel's workload, trauma exposure, and health with the cortisol, endocannabinoid, and N-acylethanolamine concentrations in their hair.

Alexander Behnke, Alexander Karabatsiakis, Aniko Krumbholz, Sarah Karrasch, Gustav Schelling, Iris-Tatjana Kolassa +1 more

In their line of duty, Emergency Medical Services (EMS) personnel are exposed to chronically stressful working conditions and recurrent traumatic events, which increase their risk for detrimental health outcomes. Here, we investigated whether this risk is due to altered regulation of the hypothalamus-pituitary-adrenal (HPA) axis and the endocannabinoid system. Therefore, 1 cm hair strands were collected from a coh…

Scientific Reports