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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
4 articles
Newest firstBackgroundEscherichia coli bloodstream infections (BSIs) have been under mandatory surveillance in the UK for fifteen years, but cases continue to rise. Systematic searches of all features present within electronic healthcare records (EHRs), described here as an EHR-wide association study (EHR-WAS), could potentially identify under-appreciated factors that could be targeted to reduce infections. MethodsWe used dat…
Open article record in new tab ↗ObjectiveElectronic Health Records (EHRs) provide information to explore those at risk of various diseases, though studying entire populations is limited by data availability, potentially introducing biases. We compared different samples, varied by type of hospital contact, to assess the impact on missing data and model results. Materials and MethodsUsing Escherichia coli bloodstream infections as a case study, we…
Open article record in new tab ↗BackgroundDecisions regarding the continued need for control measures to contain the spread of SARS-CoV-2 rely on accurate and up-to-date information about the number of people and risk factors for testing positive. Existing surveillance systems are not based on population samples and are generally not longitudinal in design. MethodsFrom 26 April to 19 September2020, 514,794 samples from 123,497 individuals were c…
Open article record in new tab ↗BackgroundThe incidence of Escherichia coli bloodstream infections (EC-BSIs), particularly those caused by antibiotic-resistant strains, is increasing in the UK and internationally. This is a major public health concern but the evidence base to guide interventions is limited.\n\nMethodsIncidence of EC-BSIs and E. coli urinary tract infections (EC-UTIs) in one UK region (Oxfordshire) were estimated from anonymised…
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