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Research Article 2013CC BYFree full text

Delta-9-Tetrahydrocannabinol-Induced Dopamine Release as a Function of Psychosis Risk: 18F-Fallypride Positron Emission Tomography Study

Rebecca Kuepper, Jenny Ceccarini, Johan Lataster, Jim van Os, Marinus van Kroonenburgh, Joop M. A. van Gerven +3 more

Cannabis use is associated with psychosis, particularly in those with expression of, or vulnerability for, psychotic illness. The biological underpinnings of these differential associations, however, remain largely unknown. We used Positron Emission Tomography and 18F-fallypride to test the hypothesis that genetic risk for psychosis is expressed by differential induction of dopamine release by Δ9-THC (delta-9-tetr…

PLoS ONE PubMed Central Open Access

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Research Article 2010CC BY-NCFree full text · non-commercial reuse

Acute effects of MDMA (3,4-methylenedioxymethamphetamine) on EEG oscillations: alone and in combination with ethanol or THC (delta-9-tetrahydrocannabinol)

Marieke M. Lansbergen, Glenn J. H. Dumont, Joop M. A. van Gerven, Jan K. Buitelaar, Robbert-Jan Verkes

RationaleTypical users of 3,4-methylenedioxymethamphetamine (MDMA or “ecstasy”) are polydrug users, combining MDMA with alcohol or cannabis [most active compound: delta-9-tetrahydrocannabinol (THC)].ObjectivesThe aim of the present study was to investigate whether co-administration of alcohol or THC with MDMA differentially affects ongoing electroencephalogram (EEG) oscillations compared to the administration of e…

Psychopharmacology PubMed Central Open Access

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