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Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
Loading articles data…
Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
5 articles
Newest firstBackgroundTongue swabs (TS) offer a promising alternative to sputum-based molecular testing for tuberculosis. As part of the Tongue Swab Yield (TSwaY) study, we assessed the cost and cost-effectiveness of integrating TS-based testing using MiniDock MTB (Guangzhou Pluslife Biotech Co., Ltd., China) into primary healthcare in four high-burden countries. MethodsCost data were collected from primary healthcare facilit…
Open article record in new tab ↗BackgroundTuberculosis (TB) diagnosis typically relies on testing sputum samples, but children often cannot produce sputum. Our review investigated the collection of self-expectorated and induced sputum, and alternative methods of sampling including gastric and nasopharyngeal aspirates, among children evaluated for presumed TB in healthcare facilities. MethodsWe searched PubMed, Embase, Cochrane Library, Web of Sc…
Open article record in new tab ↗BackgroundThe diagnosis of tuberculosis (TB) typically relies on being able to produce a sputum sample for microbiological testing. However, sputum scarcity, the inability to self-expectorate an adequate sputum sample for TB testing, is a well-known concern. Our systematic review and meta-analysis investigated the proportion of sputum scarcity among adolescents and adults being evaluated for presumptive TB in heal…
Open article record in new tab ↗BackgroundTimely and appropriate diagnosis and treatment are key to end tuberculosis (TB). Incorporating users preferences when implementing decentralized strategies for diagnosis may facilitate scale-up and impact. This qualitative study embedded within a cluster randomized controlled trial explored the values and preferences of multiple stakeholders regarding a TB diagnostic strategy using the Truenat platform,…
Open article record in new tab ↗BackgroundRecent technological and radiological advances have renewed interest in using X-rays to screen and triage people with tuberculosis (TB). The miniaturization of digital X-ray (DXR), combined with automatic interpretation using computer-aided detection (CAD) software can extend the reach of DXR screening interventions for TB. This qualitative study assessed early implementers experiences and lessons learne…
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