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Author: Anders B. Davidsen

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Research Article 2022CC BYCC BY allows this article to remain publicly readable here. Any reuse must still follow the recorded source terms.Free full text

In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats.

David Fabregat-Safont, María Mata-Pesquera, Manuela Barneo-Muñoz, Ferran Martinez-Garcia, Marie Mardal, Anders B. Davidsen +3 more

Synthetic cannabinoids receptor agonists (SCRAs) are often almost completely metabolised, and hence their pharmacokinetics should be carefully evaluated for determining the most adequate biomarker in toxicological analysis. Two structurally related SCRAs, AMB-FUBINACA and AMB-CHMICA, were selected to evaluate their in vivo metabolism and pharmacokinetics using male Sprague-Dawley rats. Brain, liver, kidney, blood…

Communications Biology Europe PMC↗

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