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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
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Readable research linked to original sources
Browse normalized, publication-ready research with direct links to its evidence and source.
2 articles
Newest firstHighlights What are the main findings? The susceptibility of rats to develop epileptic seizures after experiencing Status Epilepticus (seizure threshold) can be determined through the discrete administration of subconvulsive doses of pentylenetetrazol.Subchronic treatment (14 days) with Cannabidiol after Status Epilepticus does not modify the seizure threshold and increases several SE comorbidities such as the pos…
Open article record in new tab ↗Despite the constant development of new antiepileptic drugs (AEDs), more than 30% of patients develop refractory epilepsy (RE) characterized by a multidrug-resistant (MDR) phenotype. The "transporters hypothesis" indicates that the mechanism of this MDR phenotype is the overexpression of ABC transporters such as P-glycoprotein (P-gp) in the neurovascular unit cells, limiting access of the AEDs to the brain. Recent…
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