Magnetic Molecularly Imprinted Polymers for the Separation and Enrichment of Cannabidiol from Hemp Leaf Samples
Abstract Cannabidiol (CBD) has attracted immense attention due to its excellent clinical effects in the treatment of various diseases. However, rapid and accurate extraction of CBD from hemp plant concentrates remains a challenge. Thus, novel magnetic molecularly imprinted polymers (CBD-MMIPs) with specific recognizing capability for CBD were synthesized using ethylene glycol dimethacrylate as the cross-linker, CBD as the template, methacrylic acid as the functional monomer, azobisisobutyronitrile as the initiator, and Fe3O4 nanoparticles modified with SiO2 as the magnetic carrier. The
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