Development of a plant-produced recombinant monoclonal antibody against Δ-9-tetrahydrocannabinol (Δ9-THC) for immunoassay application

Abstract This is the first report of the production of anti- Δ9-THC mAb in N. benthamiana which are the cost-effective and rapidly production platform. Moreover, plant-produced mAb provide the efficiency against Δ9-THC and it can be applied for the further immunoassay application. Article type: Research Article Keywords: Plant-produced mAb, Transient expression, (-)-Δ 9-tetrahydrocannabinol (Δ9-THC), Immunoassay Authors: Wanuttha Boonyayothin, Khwanlada Kobtrakul, Petlada Khositanon, Sornkanok Vimolmangkang, Waranyoo Phoolcharoen Affiliations: Center of Excellence in Plant-Produced Pharmaceuticals, Chulalongkorn University, Bangkok, Thailand; Pharmaceutical Sciences and