R‐hydroxynitrile lyase from the cyanogenic millipede, Chamberlinius hualienensis—A new entry to the carrier protein family Lipocalines

Abstract We determined the X‐ray crystallographic structure of a unique hydroxynitrile lyase from the cyanogenic millipede, Chamberlinius hualienensis, and elucidated the reaction mechanism. We revealed that it belongs to the lipocalins, a family of proteins active in the transport small hydrophobic molecules. It is one of a few lipocalins with enzyme activities. This addition expands the evolutionary relationship of the enzyme to a new family of proteins. Article type: Research Article Keywords: catalytic mechanism, crystal structure, hydroxynitrile lyase, lipocalin family,