An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia

Abstract Supplemental Digital Content is Available in the Text. This experimental highly controlled trial in 20 patients with fibromyalgia shows that the cannabinoid THC, but not CBD, is effective in the treatment of fibromyalgia pain. Article type: Research Article Keywords: Cannabis, Chronic pain, Fibromyalgia, Pharmacokinetics, THC, CBD, Placebo cannabis, Pain models Authors: Tine van de Donk, Marieke Niesters, Mikael A. Kowal, Erik Olofsen, Albert Dahan, Monique van Velzen Affiliations: Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands; Bedrocan