Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

Abstract Low dose of cannabidiol ameliorates mechanical allodynia and anxious behavior and restores impaired serotonergic transmission in a neuropathic pain model in rats. Article type: Research Article Keywords: Cannabidiol, Pain, Dorsal raphe, Electrophysiology, Anxiety Authors: Danilo De Gregorio, Ryan J. McLaughlin, Luca Posa, Rafael Ochoa-Sanchez, Justine Enns, Martha Lopez-Canul, Matthew Aboud, Sabatino Maione, Stefano Comai, Gabriella Gobbi Affiliations: Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, QC, Canada; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA,