Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis

Abstract The nonpsychoactive cannabis-derivative cannabidiol (CBD) reduced nociceptor activity and pain in end-stage osteoarthritis. Prophylactic treatment with CBD prevented joint neuropathy and chronic neuropathic pain. Article type: Research Article Keywords: Cannabinoids, Osteoarthritis, Pain, Neuropathy, Inflammation Authors: Holly T. Philpott, Melissa O’Brien, Jason J. McDougall License: Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain. CC BY-NC-ND 4.0 This is an open-access article distributed under the terms of