Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development

Abstract Supplemental Digital Content is Available in the Text. Endocannabinoid signalling within brainstem centres that control top-down pain control changes significantly in early life in both rodents and humans. Article type: Research Article Keywords: Pain, RVM, PAG, Development, Postnatal, Endocannabinoid, Descending control Authors: Charlie H-T. Kwok, Ian M. Devonshire, Amer Imraish, Charles M. Greenspon, Stevie Lockwood, Catherine Fielden, Andrew Cooper, Stephen Woodhams, Sarir Sarmad, Catherine A. Ortori, David A. Barrett, David Kendall, Andrew J. Bennett, Victoria Chapman, Gareth J. Hathway