Topical analgesics for neuropathic pain: an evidence-informed guide for the practicing clinician

Abstract Objective: To evaluate available evidence for the efficacy and safety of topical analgesics for neuropathic pain and to offer treatment guidance. Methods: An expert panel searched PubMed (Medline) and reference lists of published articles for available literature assessing 8 categories of topical analgesics used to treat various neuropathic pain conditions. The panel rated the level of analgesic efficacy evidence for each treatment and considered safety, ease of use, and cost. The degree of consensus on the recommendations among the