Exploring the chemical space around Cannabis sativa L. leaves as a source of bioactive compounds of pharmaceutical interest

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-39088-0. Article type: Research Article Keywords: Leaves, Polyphenols, Cannabinoids, Policosanols, Squalene, Biochemistry, Chemistry, Drug discovery, Plant sciences Authors: Matilde Marani, Aurora Camola, Caterina Fantino, Virginia Brighenti, Massimo Tacchini, Maria Eleonora Foletti, Daniele Merli, Gianni Sacchetti, Federica Pollastro, Federica Pellati Affiliations: https://ror.org/02d4c4y02grid.7548.e0000 0001 2169 7570Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103, Modena, 41125 Italy; https://ror.org/04387x656grid.16563.370000 0001 2166 3741Department of Pharmaceutical Sciences, University of