Cannabis use and psychotic-like experiences in the All of Us Research Program

Abstract Background and Hypothesis: Cannabis use has been linked to psychotic-like experiences (PLEs). Amid increasing legalization, we examined the extent to which cannabis use is associated with PLEs after adjusting for other risk factors in a contemporary United States sample. Study Design: We performed a cross-sectional analysis of self-reported cannabis use and four types of self-reported PLEs (auditory and visual perceptual distortions, referential ideation, and persecutory ideation) in the population-based biobank, the All of Us Research Program release 8 (maximum